Scientific Topics

The 5th International One Health Congress welcomes the submission of abstracts on the following topics.
All abstract authors are asked to choose a scientific topic during the submission process.

Click on the topic of your choice for a short introduction.

 

  • Pathogen discovery


  • Investigation of pathogen origin, cross-species transmission and pathogen-host interface is highly important to understand the triggers for and to reduce the risk of zoonotic disease outbreaks. This session is expected to include presentations in the following areas: novel technological advances including molecular and serological platforms as well as improved methods for pathogen isolation and characterization; examples of pathogen discovery/characterization using one-health approach; study design and/or international collaborations in pathogen discovery and surveillance studies; and outbreak investigation in human, livestock or wildlife populations.


  • Surveillance and early detection

  • This session will focus on the surveillance and early detection of human and animal pathogens that harbour the potential to cross species barriers, with an emphasis on the creation of early outbreak detection strategies, allowing for containment at the source.


  • Diagnostics


  • There are many benefits to accrue in the One Health arena through the use of standardized and harmonized diagnostic assays in terms of sharing data across the different disciplines and sectors, in terms of operating programs taking a One Health approach and in terms of sharing or utilizing test facilities and capabilities. This session will present a series of presentations that will describe where a One Health diagnostic approach has achieved increased value and benefit through cross sectorial understanding and interpretation, the use of a shared testing facility or capability or simply through agreement on a common testing approach across species and sectors. It will consider issues on test validation, harmonisation and quality assurance when used across species and sectors.


  • Intervention strategies

  • Types of presentations:

    - Studies that illustrate the benefits of a One Health approach to interventions for control, prevention or elimination of diseases
    - Approaches to identifying, designing and evaluating One Health interventions
    - Opportunities for and challenges of developing and implementing integrated interventions that tackle multiple disease problems
    - Public health interventions targeted at (a) animal reservoirs, (b) vectors, and/or (c) the environment
    - Approaches to interventions for optimising ecosystem health outcomes


  • Social science and politics

  • This session will cover aspects of social and cultural dimensions important to One Health. It will include various socio-ecological and socio-economic aspects of community involvement, and the role of communities in protection of the environment; and in surveillance, disease detection, risk assessment and outbreak response. A particular focus of the congress will be underserved communities, so abstracts concerned with issues associated with First Nations will be highly regarded.


  • Pathogenesis

  • More information will follow...


  • Drivers for emerging diseases

  • More information will follow...


  • One Health in underprivileged communities


  • Under-served communities, whether in terms of global economy (i.e. developing versus industrialized countries) or in-country marginized communities, tend to be more exposed and vulnerable to infectious diseases. In urban centres, they tend to live in overcrowded neighbourhoods with poor sanitation and housing. In rural areas, they tend to live in remote areas far from urban centres where services are located; they live in close proximity to animals, including and especially, sharing relatively harsh ecosystems with wildlife. These conditions favour the persistence or transmission of pathogens, including newly recognized pathogens of pandemic potential. This session will explore the social and environmental settings that exacerbate the emergence, exposure and vulnerability of under-served communities to infectious diseases, especially those of a zoonotic nature. It will also examine fit-for-purpose science and technologies that enhance early detection and identification of disease events at the community level and across the human and animal health systems, conventional or unusual, and social culture sensitive interventions for effective control or elimination of both epidemic and the so-called neglected tropical diseases.


  • Vaccines


  • The congress will have two sessions dedicated to this topic. The first session focuses on recent advancements in the development of vaccines for humans and animals. This session will highlight new developments in vaccine development including vaccines for emerging diseases, specific age groups, niche populations, novel adjuvants, and novel routes of administration.
    The second session focuses on food safety vaccines, i.e. on vaccines as alternatives for antibiotics, novel vaccine strategies including vaccination of food producing animals for the benefit of the consumer, and reduction of food borne diseases through vaccination.


  • Infectious diseases from an ecohealth perspective


  • The origins of and solutions to zoonotic diseases are often found in the relationships between people, animals, and their shared environment. Ecosystem approaches to health (ecohealth) address these relationships by concurrently examining the biological, physical, and social environments and relates their interrelations to health outcomes.

    Two sessions will focus on infectious diseases from an ecohealth perspective. The first session seeks presentations demonstrating how a socio-ecological perspective can yield evidence to inspire action to prevent or control zoonotic diseases in people and/or animals. The session will emphasize presentations that deal with how to enable and support sustainable solutions that support the health of people, animals and their shared environment at the same time. Presenters are encouraged to discuss how to evaluate the benefits of ecohealth as an approach to mobilizing zoonotic disease research to action.

    The second session will continue the general theme established in the earlier, companion session, but will focus more on the ecological underpinnings that drive disease emergence, establishment, and spread, and will explore factors that might disturb the ecological balance of these drivers.


 

  • Use of antibiotics in human and animals, in food and agriculture and the link to AMR and environmental impact

  • Types of presentations:

    - Description of national systems to monitor antimicrobial use in agriculture and/or in human health
    - National or other systems for surveillance of AMR in animals, food or humans
    - Integrated systems for surveillance of antimicrobial use and AMR across sectors
    - Investigations describing AMR occurrence and/or development in animals, food or humans aimed at assessing human health risk
    - Investigations describing occurrence and/or development of AMR in the environment
    - Investigations describing interactions between AMR in microbiomes related to environment, animals for food production, food and humans
    - Investigations describing antimicrobial use patterns in agri- and aquaculture (including use of antimicrobial growth promotors) and the effect on AMR occurrence
    - Investigations describing antimicrobial use patterns in the human health sector and the effect on AMR occurrence


  • Genomic epidemiology / evolution of AMR transmission

  • Antimicrobial resistance is rapidly increasing and represents a large threat for both human and animal welfare. Resistance knows of no boundaries which make a sectored approach for the understanding and not the least for seeking mitigating solutions to this threat insufficient. Instead, AMR must be seen, investigated and understood using a One Health approach. This session seeks presentations that investigate the genomic epidemiology of resistance as well as the evolution of AMR transmission with emphasis on epidemiological markers, successful strains and/or their interspecies transmission using a One Health approach. The presentations should put attention on setting the epidemiology and the risk in context to the burden of resistance within the individual sectors as well as for trans-sectorial transmission.


  • Real life applications of whole genome sequencing

  • Whole Genome Sequencing (WGS) might arguably be the most significant advance in diagnostic microbiology and surveillance since the advent of in vitro culture. WGS is increasingly being employed for outbreak investigation and bacterial genomic epidemiology, species identification, and to a lesser extent, culture independent microbiology and susceptibility testing. This session invites  presentations on the application and impact of WGS in routine microbiology laboratories, as well as for patient care, outbreak detection (human, animal, food), index tracing and infection control. Current hurdles associated with use of WGS for real-time applications and possible solutions will also be discussed.


  • Prevalence and surveillance of resistance

  • This session will focus on reservoirs of resistance in the environment and animals, and on new methods that can be used in surveillance.


  • Novel strategies for AMR interventions / preparedness

  • A One Health approach to antimicrobial resistance requires taking human, animal, and environmental health into consideration. Whole-genome sequencing is essential in understanding the etiology and epidemiology of AMR. Antibiotics have saved millions of lives but they have also come with costs including adversely affecting human microbiomes and potentially altering microbial ecosystems. Alternatives must be examined. For example, bacteriophages are the natural foes of bacteria and are the most prevalent bioforms on the planet. There are challenges with them, but they have the potential to revolutionize the practice of medicine and agriculture in the 21st century. This session focuses on novel strategies to address AMR.


  • Alternative approaches to tackling resistant infections

  • Antibiotics have revolutionized modern medicine but after more than 70 years of widespread use, effectiveness is decreasing and the pace of discovery has not kept up with the pace of microbial resistance. New, innovative approaches to tackling resistant infections are urgently needed. Emphasizing a One Health approach, this session seeks presentations demonstrating promising, novel ways to address resistant infections in humans, animals, and the environment. From antimicrobial peptides, antibodies, probiotics, and bacteriophages to immune stimulation, vaccines and gene editing, the session will emphasize a broad approach to address resistant infections. Presenters are encouraged to discuss the feasibility of informative clinical trials, likelihood and consequences of resistance, level of current research activity, and activities that will enable validation and progression. While recognizing the gaps in available data in this emerging field, the session will provide an assessment of promising alternatives to antibiotics and their potential.


  • Rapid diagnostics

  • Rapid diagnostic techniques for detection of antibiotic resistance both including resistance in bacterial isolates and directly in clinical samples and those for investigation of colonization with resistant microorganisms. New (rapid) methods on antimicrobial susceptibility testing. Implementation of rapid diagnosis techniques in stewardship programs.